By Stephany Porter, ND, FABNO Do nightshades make joint pain worse? As a Naturopathic Doctor, the practice of medicine is a journey we take where each day brings new lessons.  I recently had a patient who had been avoiding nightshades and seeing incredible improvement then, all of the sudden her joint pain increased.  Upon a thorough review of her diet, she disclosed she had been adding goji berries to her smoothies at breakfast due to its high antioxidant and health benefits